Tissue non-specific alkaline phosphatase inhibitors and uses thereof for treating vascular calcification
作者： Eduard Sergienko , Jose Luis Millan
DOI:
关键词: Vascular calcification 、 Pathology 、 Arterial calcification 、 Alkaline phosphatase 、 Chemistry 、 Non specific
摘要: Disclosed herein are compounds that tissue-nonspecific alkaline phosphatase inhibitors. The disclosed used to treat, prevent, or abate vascular calcification, arterial calcification and other cardiovascular diseases.
lens.org 参考文章(79)
Kim Km, Calcification of matrix vesicles in human aortic valve and aortic media. Federation proceedings. ,vol. 35, pp. 156- 162 ,(1976)
Pierre Voisine, François Dagenais, Patrick Mathieu, Andrée Pépin, Nadia Savard, Rahoul Shetty, Calcification of human valve interstitial cells is dependent on alkaline phosphatase activity. Journal of Heart Valve Disease. ,vol. 14, pp. 353- 357 ,(2005)
José Luis Millán, Mammalian Alkaline Phosphatases: From Biology to Applications in Medicine and Biotechnology ,(2006)
B G Taal, , H Van Tinteren, F A N Zoetmulder, Adjuvant 5FU plus levamisole in colonic or rectal cancer: improved survival in stage II and III. British Journal of Cancer. ,vol. 85, pp. 1437- 1443 ,(2001) , 10.1054/BJOC.2001.2117
Michael Mezei, Multiphase liposomal drug delivery system ,(1985)
Akihiko Okawa, Isao Nakamura, Sumio Goto, Hideshige Moriya, Yusuke Nakamura, Shiro Ikegawa, Mutation in Npps in a mouse model of ossification of the posterior longitudinal ligament of the spine Nature Genetics. ,vol. 19, pp. 271- 273 ,(1998) , 10.1038/956
Marcus Eugene Kehrli, Ernest S. Pfizer Global Res. Dlp. Hamanaka, Substituted Heteroaryl- and Phenylsulfamoyl Compounds ,(2005)
Marvin J. Meyers, Kun K. Wu, Serena Marie Mershon, Shridhar G. Hegde, Ingrid P. Buchler, Kassoom Nacro, Matthew J. Graneto, Cathleen E. Hanau, Shuang Liu, Acyclic pyrazole compounds for the inhibition of mitogen activated protein kinase-activated protein kinase-2 ,(2003)
Alfonso R. Gennaro, Remington: The Science and Practice of Pharmacy ,(2003)
Saburo Matsuda, Hiroshi Miura, Akira Suzuki, Takashi Ohsawa, Method of preparing a controlled release liquid pharmaceutical composition ,(1976)