Betablocker treatment in diabetes mellitus.

摘要: Sawicki PT, Siebenhofer A (St Franziskus Hospital in Cologne, Germany; Karl-Franzens University Graz, Austria). Betablocker treatment diabetes mellitus (Review). J Intern Med 2001; 250: 11–17. Objectives. Betablockers have been convincingly shown to reduce total and cardiovascular morbidity mortality of hypertensive diabetic patients. In patients, after myocardial infarction, these agents confer a twice as high protective effect when compared non-diabetic However, most paradoxically, betablocking are used less frequently diabetes. Control hypertension is insufficient the probably because combination antihypertensive including betablockers needed sufficiently control blood pressure but not The fear betablocker-associated side effects may be partly responsible for frequent mono-therapy resulting poor quality among patients. Design. We performed an analysis literature assess whether possible adverse metabolic effects, higher risk hypoglycaemia or nephroprotective s1-selective could justify reticence prescribing patients. Results. thorough review does indicate that important on glucose metabolism, prolong mask hypoglycaemic symptoms. nephropathy, angiotensin converting enzyme inhibitors. Conclusions. unnecessary prescription contribute