Pharmacogenomics of Human UDP-Glucuronosyltransferases and Irinotecan Toxicity
作者： Robert H. Tukey , Christian P. Strassburg , Peter I. Mackenzie
DOI: 10.1124/MOL.62.3.446
关键词: Pharmacogenomics 、 SUPERFAMILY 、 Gene 、 Pharmacology 、 Irinotecan 、 Toxicity 、 Biology 、 Udp glucuronosyltransferases 、 Tissue specific 、 Biochemistry
摘要: The human UDP-glucuronosyltransferases (UGTs) represent a superfamily of proteins ([Mackenzie et al., 1997][1]) that are attracting much interest because their extensive polymorphic patterns gene and tissue specific expression 2000][2]; [Tukey Strassburg, 2000][3]).
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