Reduced vascular compliance as a marker for essential hypertension.

摘要: In 38 patients with established essential hypertension and 32 age-matched normotensive control subjects proximal distal arterial compliance were determined by computer-based assessment of the diastolic decay a brachial tracing modified Windkessel model circulation. hypertensive compared to mean pressure was 25% higher (P less than .001), systemic vascular resistance 23% .01), 19% lower 72% .001). The reduction in highly age-dependent. youngest age range (45 54 years) little overlap appeared between groups, whereas oldest studied (65 75 comparably low two groups. Thus, provides sensitive specific marker for abnormal vasculature associated may be particularly useful identifying disease young individuals borderline blood pressure.