Chemical Insights Into the Synthetic Chemistry of Quinazolines: Recent Advances.

摘要: In medicinal chemistry, one of the most significant heterocyclic compounds are quinazolines, possessing broad range biological properties such as anti-bacterial, anti-fungal, anti-HIV, anti-cancer, anti-inflammatory, and analgesic potencies. Owing to its numerous potential applications, in past two decades, there is an increase importance designing novel exploring promising routes synthesize investigating different seeking for applications quinazolines. The present review article describes synthesis quinazolines via eco-friendly, mild, atom-efficient, multi-component synthetic strategies reported literature. discussion divided into parts per key methods involved formation quinazoline skeletons, aiming provide readers effective methodology a better understanding. Consideration has been taken cover recent references. Expectedly, will be advantageous future research synthesizing developing more approaches.