Relation of heart rate and blood pressure turbulence following premature ventricular complexes to baroreflex sensitivity in chronic congestive heart failure.

摘要: Abstract Reduced heart rate variability (HRV) and attenuated baroreflex sensitivity (BS) after myocardial infarction in patients with chronic congestive failure (CHF) are associated poor prognosis. Recent studies have shown that a large proportion of the prognostic power from HRV measurements is localized turbulence immediately ventricular premature complexes. The mechanism remains unknown. In present study, we explore its relation to BS. 45 CHF ≥3 ectopic beats 30-minute period, RR interval continuous, noninvasive blood pressure (BP) were studied at rest. response an beat, average was 9.4 ms/beat (SD 6.1). Mean BP 0.72 mm Hg/beat 0.56). Using ratio slopes estimate BS showed good agreement (r = 0.67, p α ). This attributable marked correlation between 0.70, 0.1, NS). Twenty-nine percent had postectopic pulsus alternans, mean decay time 1.4 0.5). presence alternans significantly lower slope (6.3 [SEM 1.0] vs 10.7 1.2] ms/beat, 0.03). Thus, effective measure baroreflex, correlating strongly standard measure. because it rate, rather than BP, beat conveys information relevant measurement.