Antimicrobial Photodynamic Therapy in the Treatment of Oral Candidiasis in HIV-Infected Patients
作者： Agnes Roberta Scwingel , Ana Rita Pinheiro Barcessat , Silvia Cristina Núñez , Martha Simões Ribeiro
关键词: Methylene blue 、 Surgery 、 Medicine 、 Photosensitizer 、 Laser therapy 、 Gastroenterology 、 Hiv infected patients 、 Antimicrobial 、 Light source 、 Photodynamic therapy 、 Fluconazole 、 Internal medicine
摘要: Abstract Objective: Antimicrobial photodynamic therapy (aPDT) has been used to combat local infections, and it consists of the combination a photosensitizer, light source, reactive oxygen species (ROS) kill microbial cells. In this study, we evaluated effectiveness aPDT in treatment candidiasis HIV-infected patients. Methods: Twenty-one patients were divided into three groups. Control group (CG) was treated with conventional medication for (fluconazole 100 mg/day during 14 days). Laser (LG) subjected low-level laser (LLLT), wavelength 660 nm, power 30 mW, fluence 7.5 J/cm2, contact mucosa 10 sec on affected point. An (aPDTG) aPDT, that is, low-power methylene blue 450 μg/mL. Pre-irradiation time 1 min. Parameters irradiation same ones as LG, single irradiated. Patients clinically culture analysis w...
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