Correlates and predictors of disability in vulnerable US Hispanics with rheumatoid arthritis

作者: George A. Karpouzas , Soha Dolatabadi , Rosalinda Moran , Ning Li , Perry M. Nicassio

DOI: 10.1002/ACR.21689

关键词: MedicineArthritisSeverity of illnessPhysical therapyVisual analogue scaleCross-sectional studyRheumatoid arthritisDepression (differential diagnoses)FibromyalgiaArthrodesis

摘要: Objective US Hispanics with rheumatoid arthritis experience worse functional outcomes compared to whites. The determinants of disability, however, are not well established in large Hispanic cohorts. In the present report, we identified factors associated disability a cross-sectional design, and evaluated their individual contributions over time. Methods Two hundred fifty-one subjects from single center were evaluated. Disease activity, serologies, radiographs, treatments, irreversible articular damage (defined as subluxation, arthrodesis, fusion, or prosthesis), joint replacement surgeries recorded. Self-reported (Health Assessment Questionnaire index), patient pain by visual analog scale, depression assessments collected. Cross-sectional identified, effects on future subgroup 114 patients assessed 6 months later. Results Six parameters independently related cross-sectionally: was strongest (P < 0.0001), followed damage, disease depression, age, fibromyalgia 0.03 for all). Baseline predicting later included, decreasing significance, = 0.004), (all P 0.04). Conclusion In analysis, self-reported had relationship disability; such activity more important disability. Most these amenable targeted interventions should be addressed an effort improve outcomes.

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