In vitro resistance of articular chondrocytes to 5-Aminolevulinic acid based photodynamic therapy.

作者: Rainer J. Egli , Agostino Di Criscio , Axel Hempfing , Ralf Schoeniger , Reinhold Ganz

DOI: 10.1002/LSM.20625

关键词: Synovial CellAnatomyChemistryArthritisIn vivoChondrocyteIn vitroCartilageAggrecanMolecular biologyCitrate synthase

摘要: … Upon uptake, 5-ALA (prodrug) is converted along the heme synthesis pathway to the photosensitive intermediate protoporphyrin IX (PpIX; drug). A prerequisite for the accumulation of …

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