Comparison of the effects of antidepressants and their metabolites on reuptake of biogenic amines and on receptor binding.

作者: Connie Sánchez , John Hyttel

DOI: 10.1023/A:1006986824213

关键词: FluoxetineCitalopramSertralineMedicineLofepraminePharmacologyFluvoxamineVenlafaxineAntidepressantBupropion

摘要: 1. The present survey compares the effects of antidepressants and their principal metabolites on reuptake biogenic amines receptor binding. following were included in study: tricyclic amitriptyline, dothiepin, lofepramine atypical antidepressant bupropion, which all have considerable market shares UK and/or US markets; selective serotonin inhibitors (SSRIs) citalopram, fluoxetine, fluvoxamine, paroxetine, sertraline; recently approved venlafaxine nefazodone.

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