Bioavailability and newer methods of delivery of phosphorothioate radioprotectors
作者： Lawrence Fleckenstein , Nollie F. Swynnerton , Thomas M. Ludden , Donald J. Mangold
DOI: 10.1016/0163-7258(88)90062-9
关键词: Pharmacology 、 Bioavailability 、 Chemistry 、 Pharmacology (medical)
摘要:
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sci-hub.se 参考文章(24)
H.G. France, R.L. Jirtle, C.M. Mansbach, Intracolonic WR 2721 protection of the rat colon from acute radiation injury. Gastroenterology. ,vol. 91, pp. 644- 650 ,(1986) , 10.1016/0016-5085(86)90634-7
Marie M. Grenan, David E. Davidson, Thomas R. Sweeney, Biological Characteristics of Some Improved Radioprotectors ,(1980)
D. J. Mangold, N. F. Swynnerton, C. W. Lew, E. P. McGovern, T. M. Ludden, Investigations Concerning Hydrolysis and Stabilization of Antiradiation Compounds Defense Technical Information Center. ,(1985) , 10.21236/ADB109071
Jean DeBrohun Butler, William A. Gahl, Frank Tietze, Cystine depletion by WR-1065 in cystinotic cells. Mechanism of action. Biochemical Pharmacology. ,vol. 34, pp. 2179- 2185 ,(1985) , 10.1016/0006-2952(85)90415-0
N F Tabachnik, A Cerami, P Blackburn, C M Peterson, Protein binding of N-2-mercaptoethyl-1,3-diaminopropane via mixed disulfide formation after oral administration of WR 2721. Journal of Pharmacology and Experimental Therapeutics. ,vol. 220, pp. 243- 246 ,(1982)
Paula M. Calabro-Jones, Robert C. Fahey, Geraldine D. Smoluk, John F. Ward, Alkaline phosphatase promotes radioprotection and accumulation of WR-1065 in V79-171 cells incubated in medium containing WR-2721. International Journal of Radiation Biology. ,vol. 47, pp. 23- 27 ,(1985) , 10.1080/09553008514550041
Nollie F. Swynnerton, Belinda K. Huelle, Donald J. Mangold, Thomas M. Ludden, A method for the combined measurement of ethiofos and WR-1065 in plasma: Application to pharmacokinetic experiments with ethiofos and its metabolites☆ International Journal of Radiation Oncology Biology Physics. ,vol. 12, pp. 1495- 1499 ,(1986) , 10.1016/0360-3016(86)90202-6
Jerzy Sarosiek, Amalia Slomiany, Bronislaw L. Slomiany, Retardation of hydrogen ion diffusion by gastric mucus constituents: Effect of proteolysis Biochemical and Biophysical Research Communications. ,vol. 115, pp. 1053- 1060 ,(1983) , 10.1016/S0006-291X(83)80042-4
Nollie F. Swynnerton, Donald J. Mangold, Thomas M. Ludden, Measurement Of Ethiofos (Wr 2721) In Plasma: Preliminary Pharmaco-Kinetics in the Beagle Journal of Liquid Chromatography & Related Technologies. ,vol. 8, pp. 2675- 2687 ,(1985) , 10.1080/01483918508076598
Joe A. Niño, Donald J. Mangold, Nollie F. Swynnerton, Edward P. McGovern, An improved HPLC assay for S-2-(3-aminopropylamino)ethyl phosphorothioate (WR-2721) in plasma International Journal of Radiation Oncology Biology Physics. ,vol. 10, pp. 1521- 1524 ,(1984) , 10.1016/0360-3016(84)90494-2