Low-Level Arsenic Impairs Glucose-Stimulated Insulin Secretion in Pancreatic Beta Cells: Involvement of Cellular Adaptive Response to Oxidative Stress
作者： Jingqi Fu , Courtney G. Woods , Einav Yehuda-Shnaidman , Qiang Zhang , Victoria Wong
DOI: 10.1289/EHP.0901608
关键词: Carbohydrate metabolism 、 Type 2 diabetes 、 Oxidative stress 、 Oxidative phosphorylation 、 Internal medicine 、 Pathogenesis 、 Arsenic toxicity 、 Dose–response relationship 、 Biology 、 Endocrinology 、 Diabetes mellitus
摘要: BackgroundChronic exposure of humans to inorganic arsenic, a potent environmental oxidative stressor, is associated with incidence type 2 diabetes (T2D). A key driver in the pathogenesis T2D ...
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