Environmental and toxicological aspects of insect growth regulators.

摘要: Insect growth regulators (IGRs) are a class of new chemicals that interfere with maturation and reproduction in insects. Proposed hypotheses on the biochemical mechanism action presented herein. The environmental aspects as metabolism soils, plants, insects, animals suggest strongly these undergo rapid degradation to innocuous metabolites. toxicological properties determined for registration IGR methoprene, isopropyl (E,E)-11-methoxy-3,7,11-trimethyl-2,4-dodecadienoate, reflected no significant effects against any species tested. Toxicological evaluations swine, sheep, hamsters, rats, dogs, rabbits, guinea pigs, cattle revealed clinical signs toxicosis. Additionally, teratological studies rabbits also resulted observable at levels administered.