Biodegradable Polymer-Based Scaffolds for Bone Tissue Engineering
作者： Naznin Sultana
DOI:
关键词: Composite material 、 Polymer 、 Biodegradable polymer 、 Chemical engineering 、 Tissue engineering 、 Materials science 、 Emulsion 、 Crystallization of polymers 、 Porosity 、 Bioceramic 、 Composite number
摘要: This chapter reports the emulsion freezing/freeze-drying technique for formation of three-dimensional porous scaffolds bone tissue engineering applications. Poly(hydroxybutyrate-co-hydroxyvalerate) (PHBV), which is a natural, biodegradable polymer, was used as main polymer fabricating various scaffolds. Nano-sized hydroxyapatite (HA), widely bioceramic, incorporated in order to obtain bioactive (i.e., osteoconductive) composite The focused two areas: (1) investigations into scaffold fabrication using and influence processing parameters on PHBV scaffolds, HA/PHBV HA-containing PHBV/PLLA blend-based scaffolds; (2) evaluation different terms their structure, porosity, pore size, crystallinity, compressive mechanical properties, vitro biodegradation behavior biological performance.
springer.com
amazon.com
openlibrary.org参考文章(18)
A.-C. Albertsson, Degradable Aliphatic Polyesters ,(2010)
秀人 辻, Degradation of poly (lactide)-based biodegradable materials Nova Science Publishers. ,(2008)
Lorna J. Gibson, Michael F. Ashby, Cellular Solids: Structure and Properties ,(1988)
Murugan Ramalingam, Ziyad Haidar, Seeram Ramakrishna, Hisatoshi Kobayashi, Youssef Haikel, Fabrication of Tissue Engineering Scaffolds Using the Emulsion Freezing/Freeze-drying Technique and Characteristics of the Scaffolds Integrated Biomaterials in Tissue Engineering. pp. 63- 89 ,(2012) , 10.1002/9781118371183.CH4
Haiyan Li, Ruilin Du, Jiang Chang, Fabrication, characterization, and in vitro degradation of composite scaffolds based on PHBV and bioactive glass. Journal of Biomaterials Applications. ,vol. 20, pp. 137- 155 ,(2005) , 10.1177/0885328205049472
Haifei Zhang, Irshad Hussain, Mathias Brust, Michael F. Butler, Steven P. Rannard, Andrew I. Cooper, Aligned two- and three-dimensional structures by directional freezing of polymers and nanoparticles Nature Materials. ,vol. 4, pp. 787- 793 ,(2005) , 10.1038/NMAT1487
Naznin Sultana, Tareef Hayat Khan, In vitro degradation of PHBV scaffolds and nHA/PHBV composite scaffolds containing hydroxyapatite nanoparticles for bone tissue engineering Journal of Nanomaterials. ,vol. 2012, pp. 1- 12 ,(2012) , 10.1155/2012/190950
Friederike von Burkersroda, Luise Schedl, Achim Göpferich, Why degradable polymers undergo surface erosion or bulk erosion. Biomaterials. ,vol. 23, pp. 4221- 4231 ,(2002) , 10.1016/S0142-9612(02)00170-9
Fanming Meng, Zhaoqi Sun, Xueping Song, Influence of annealing and UV irradiation on hydrophilicity of Ag-TiO 2 nanostructured thin films Journal of Nanomaterials. ,vol. 2012, pp. 12- ,(2012) , 10.1155/2012/310514
J KNOWLES, G HASTINGS, H OHTA, S NIWA, N BOEREE, Development of a degradable composite for orthopaedic use: in vivo biomechanical and histological evaluation of two bioactive degradable composites based on the polyhydroxybutyrate polymer. Biomaterials. ,vol. 13, pp. 491- 496 ,(1992) , 10.1016/0142-9612(92)90099-A