Chitosan based nanofibers in bone tissue engineering.

作者: K. Balagangadharan , S. Dhivya , N. Selvamurugan

DOI: 10.1016/J.IJBIOMAC.2016.12.046

关键词:

摘要: Bone tissue engineering involves biomaterials, cells and regulatory factors to make biosynthetic bone grafts with efficient mineralization for regeneration of fractured or damaged bones. Out all the techniques available scaffold preparation, electrospinning is given priority as it can fabricate nanostructures. Also, electrospun nanofibers possess unique properties such high surface area volume ratio, porosity, stability, permeability morphological similarity that extra cellular matrix. Chitosan (CS) has a significant edge over other materials graft material, CS be used alone in combination form provide structural biochemical cues acceleration regeneration. Hence, this review was aimed detailed study on its composites prepared nanofibers, their associated found suitable engineering.

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