Interaction of Rhei Rhizoma extract with cytochrome P450 3A and efflux transporters in rats.
作者： T Yokooji , T Murakami , N Mori , M Mori , M Kida
DOI:
关键词: Rhodamine 123 、 Drug metabolism 、 Glutathione 、 Efflux 、 CYP3A 、 Microsome 、 Bioavailability 、 Medicine 、 Pharmacology 、 Pharmacokinetics
摘要: … Rhei Rhizoma extract with cytochrome P450 (CYP) 3A and … , though it exerted no effect on the biliary excretion of Rho123. … ) and pH 6.0 isotonic PBS instead of Rho123 and pH 7.4 D-…
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