The Mammalian Oocyte
DOI: 10.1016/B978-0-12-397175-3.00002-8
关键词: Reproductive technology 、 Meiosis 、 Oogenesis 、 Biology 、 Somatic cell 、 Oocyte 、 Cell cycle 、 Cell biology 、 Folliculogenesis 、 Ovarian follicle
摘要: The mammalian oocyte is an extraordinary cell owing to its unique ability initiate and sustain development of a complete organism. purpose this chapter inform guide the reader through properties that allow it fulfill obligatory role in life cycle mammals. Major features cytoplasm nucleus are considered followed by coverage cellular, molecular, biochemical traits must be acquired during course oogenesis, protracted process occurring within ovarian follicle. oogenesis divided into three operationally distinct sequential stages: growth phase, pre-maturative maturative phase. Themes developed overall progress growth, pre-maturative, phases include (1) acquisition competencies meiotic cycle, (2) dialogue between surrounding somatic cells follicle assuring adequate metabolic support synchronization folliculogenesis, (3) coordination transcription, translation, posttranslational protein modifications pertaining differentiation mature relation execution fertilization early embryogenesis. experimental clinical manipulation finally discussed context assisted reproductive technologies, stem biology.
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