NMDA receptor hypofunction produces concomitant firing rate potentiation and burst activity reduction in the prefrontal cortex

作者: M. E. Jackson , H. Homayoun , B. Moghaddam

DOI: 10.1073/PNAS.0308455101

关键词: Working memoryNMDA receptorNeuroscienceMedicineElectrophysiologyLong-term potentiationPrefrontal cortexSchizophreniaStereotypy (non-human)Frontal lobe

摘要: … The aim of the present study was to define the mechanisms by which behaviorally relevant reductions in NMDA receptor function may disrupt the pattern of activity of PFC neurons. We …

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