Immunohistochemical analysis of p185 and ASL activity in pre-neoplastic lesions and intestinal mucosa of human subjects.
作者： L. Terzuoli , B. Frosi , B. Porcelli , F. Carlucci , C. Minacci
DOI: 10.1007/978-1-4615-5381-6_155
关键词: Oncology 、 Pathological 、 Intestinal mucosa 、 Colorectal cancer 、 Breast cancer 、 Chemotherapy 、 Incidence (epidemiology) 、 Somatic cell 、 Immunohistochemistry 、 Internal medicine 、 Medicine
摘要: Colorectal cancer is the second neoplasia in terms of incidence and mortality (after lung-cancer men breast women), with 20,000 new cases Italy every year 10,000 deathes. The starting point multiphasic process leading to colorectal (somatic inherited genetic alterations which involve activation onco-genes inactivation oncosuppressor genes) seems be adenomatous polyposis. Since due high our country, perspectives for early diagnosis chemotherapy, based on molecular biochemical patterns at different stages pathological process, are needed.
core.ac.uk
springer.com
sci-hub.st 参考文章(12)
L. Lorenzini, A. De Martino, W. Testi, F. Sorbellini, E. Dispensa, A. Tabucchi, F. Carlucci, F. Rosi, Behavior of enzymes involved in purine nucleotide metabolism in tumors. Advances in Experimental Medicine and Biology. ,vol. 370, pp. 213- 218 ,(1995) , 10.1007/978-1-4615-2584-4_46
George Weber, Biochemical Strategy of Cancer Cells and the Design of Chemotherapy: G. H. A. Clowes Memorial Lecture Cancer Research. ,vol. 43, pp. 3466- 3492 ,(1983)
Vicki L. Reed, Donald O. Mack, Larry D. Smith, Adenylosuccinate lyase as an indicator of breast and prostate malignancies: A preliminary report Clinical Biochemistry. ,vol. 20, pp. 349- 351 ,(1987) , 10.1016/S0009-9120(87)80085-1
C. King, M. Kraus, S. Aaronson, Amplification of a novel v-erbB-related gene in a human mammary carcinoma Science. ,vol. 229, pp. 974- 976 ,(1985) , 10.1126/SCIENCE.2992089
Jun Yokota, Kumao Toyoshima, Takashi Sugimura, Tadashi Yamamoto, Masaaki Terada, Hector Battifora, MartinJ Cline, Amplification of c-erbB-2 oncogene in human adenocarcinomas in vivo. The Lancet. ,vol. 327, pp. 765- 767 ,(1986) , 10.1016/S0140-6736(86)91782-4
GIOVANNA DIGIESI, PATRIZIO GIACOMINI, ROCCO FRAIOLI, MASSIMO MARIANI, MARIA RITA NICOTRA, ORESTE SEGATTO, PIER GIORGIO NATALI, Production and Characterization of Murine mAbs to the Extracellular Domain of Human Neu Oncogene Product GP185HER2 Hybridoma. ,vol. 11, pp. 519- 527 ,(1992) , 10.1089/HYB.1992.11.519
K. Semba, N. Kamata, K. Toyoshima, T. Yamamoto, A v-erbB-related protooncogene, c-erbB-2, is distinct from the c-erbB-1/epidermal growth factor-receptor gene and is amplified in a human salivary gland adenocarcinoma Proceedings of the National Academy of Sciences of the United States of America. ,vol. 82, pp. 6497- 6501 ,(1985) , 10.1073/PNAS.82.19.6497
Robert C. Jackson, Harold P. Morris, George Weber, Neoplastic transformation-linked alterations in adenylosuccinate synthetase activity. Biochemical and Biophysical Research Communications. ,vol. 66, pp. 526- 532 ,(1975) , 10.1016/0006-291X(75)90542-2
S M Hsu, L Raine, H Fanger, Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures. Journal of Histochemistry and Cytochemistry. ,vol. 29, pp. 577- 580 ,(1981) , 10.1177/29.4.6166661
Harold P. Morris, George Weber, Robert C. Jackson, Enzymes of the purine ribonucleotide cycle in rat hepatomas and kidney tumors. Cancer Research. ,vol. 37, pp. 3057- 3065 ,(1977)