Dissecting Transcriptional Control Networks

作者: Vijayalakshmi H. Nagaraj , Anirvan M. Sengupta

DOI: 10.1007/978-1-59745-531-2_6

关键词: DNA sequencingTranscriptional regulationSupport vector machineGenomeTranscription factorTranscription (biology)Computational biologyComputer scienceTranscriptional NetworksPromoter

摘要: Reconstructing how transcriptional networks function involves figuring out which promoters are affected by transcription factors. Searching for functional regulatory sites bound particular factors in a genome is therefore of great importance. The chapter discusses efforts at building classifiers that separate targeted from those not. We start with simple sequence based on Support Vector Machines and go to discuss integrate different kind data into the analysis.

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