Lessons learned from implementing Clostridium difficile-focused antibiotic stewardship interventions.
作者： B. Ostrowsky , R. Ruiz , S. Brown , P. Chung , E. Koppelman
DOI: 10.1086/677828
关键词: Antibiotics 、 Intervention group 、 Clostridium difficile 、 Defined daily dose 、 Antibiotic Stewardship 、 Antimicrobial stewardship 、 Intensive care medicine 、 Medicine 、 Medical prescription 、 Psychological intervention
摘要: Objective. To determine whether controlling the prescription of targeted antibiotics would translate to a measurable reduction in hospital-onset Clostridium difficile infection (CDI) rates.Design. A multicenter before-and-after intervention comparative study.Setting/participants. Ten medical centers greater New York region. Intervention group comprised 6 facilities with early antimicrobial stewardship programs (ASPs). The 4 without ASPs made up nonintervention group.Interventions/methods. Intervention identified target using case-control studies and implemented ASP-based strategies control their use. Pre- postintervention CDI rates antibiotic consumption were compared for 20-month period from June 2010 January 2012. Antibiotic usage was defined daily dose, days therapy, number courses prescribed. Comparisons used bivariate regression techniques.Results. Intervention piperacilli...
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Robert C Owens, Clostridium difficile-associated disease: changing epidemiology and implications for management. Drugs. ,vol. 67, pp. 487- 502 ,(2007) , 10.2165/00003495-200767040-00001
Naomi P O'Grady, Mary Alexander, E Patchen Dellinger, Julie L Gerberding, Stephen O Heard, Dennis G Maki, Henry Masur, Rita D McCormick, Leonard A Mermel, Michele L Pearson, Issam I. Raad, Adrienne Randolph, Robert A Weinstein, None, Guidelines for the prevention of intravascular catheter-related infections. Centers for Disease Control and Prevention. MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports / Centers for Disease Control. ,vol. 51, pp. 1- 29 ,(2002)
Matthew D. Redelings, Frank Sorvillo, Laurene Mascola, Increase in Clostridium difficile-related mortality rates, United States, 1999-2004. Emerging Infectious Diseases. ,vol. 13, pp. 1417- 1419 ,(2007) , 10.3201/EID1309.061116
L. Clifford McDonald, Maria Owings, Daniel B. Jernigan, Clostridium difficileInfection in Patients Discharged from US Short-stay Hospitals, 1996–20031 Emerging Infectious Diseases. ,vol. 12, pp. 409- 415 ,(2006) , 10.3201/EID1203.051064
Kathleen A. Gase, Valerie B. Haley, Kuangnan Xiong, Carole Van Antwerpen, Rachel L. Stricof, Comparison of 2 Clostridium difficile Surveillance Methods National Healthcare Safely Network's Laboratory-Identified Event Reporting Module versus Clinical Infection Surveillance Infection Control & Hospital Epidemiology. ,vol. 34, pp. 284- 290 ,(2013) , 10.1086/669509
Amit S. Chitnis, Stacy M. Holzbauer, Ruth M. Belflower, Lisa G. Winston, Wendy M. Bamberg, Carol Lyons, Monica M. Farley, Ghinwa K. Dumyati, Lucy E. Wilson, Zintars G. Beldavs, John R. Dunn, L. Hannah Gould, Duncan R. MacCannell, Dale N. Gerding, L. Clifford McDonald, Fernanda C. Lessa, Epidemiology of Community-AssociatedClostridium difficileInfection, 2009 Through 2011 JAMA Internal Medicine. ,vol. 173, pp. 1359- 1367 ,(2013) , 10.1001/JAMAINTERNMED.2013.7056
Brian S. Koll, Rafael E. Ruiz, David P. Calfee, Hillary S. Jalon, Rachel L. Stricof, Audrey Adams, Barbara A. Smith, Gina Shin, Kathleen Gase, Maria K. Woods, Ismail Sirtalan, Prevention of Hospital‐Onset Clostridium difficile Infection in the New York Metropolitan Region Using a Collaborative Intervention Model Journal for Healthcare Quality. ,vol. 36, pp. 35- 45 ,(2014) , 10.1111/JHQ.12002
Naomi P. O'Grady, Mary Alexander, Lillian A. Burns, E. Patchen Dellinger, Jeffrey Garland, Stephen O. Heard, Pamela A. Lipsett, Henry Masur, Leonard A. Mermel, Michele L. Pearson, Issam I. Raad, Adrienne G. Randolph, Mark E. Rupp, Sanjay Saint, Guidelines for the Prevention of Intravascular Catheter-related Infections American Journal of Infection Control. ,vol. 39, pp. 476- 489 ,(2002) , 10.1016/J.AJIC.2011.01.003
F. C. Lessa, C. V. Gould, L. C. McDonald, Current Status of Clostridium difficile Infection Epidemiology Clinical Infectious Diseases. ,vol. 55, ,(2012) , 10.1093/CID/CIS319
R. E. Polk, C. Fox, A. Mahoney, J. Letcavage, C. MacDougall, Measurement of adult antibacterial drug use in 130 US hospitals: comparison of defined daily dose and days of therapy. Clinical Infectious Diseases. ,vol. 44, pp. 664- 670 ,(2007) , 10.1086/511640