Primary intestinal lymphoma: clinical manifestations and possible effect of environmental factors.

摘要: Lymphoma of the small intestine can occur as a late secondary manifestation disseminated lymphoma, or far less commonly, primary lesion originating in mesenteric lymph nodes [1–6]. The latter disease be further subdivided into two categories: a) Solitary lymphoma that occurs most commonly terminal ileum and is encountered more frequently young children, b) Diffuse multifocal intestinal occurring proximal primarily older age groups. In entity malabsorption has been described [3–5]. syndrome by EDELMAN et al. (1966), only rarely developed countries Western world [7]. These authors, reviewing medical literature West, were able to find 48 cases, which they regarded 32 well established 16 probable. On other hand, not rare among certain populations whose common denominator appears are under-privileged terms nutrition, hygiene care [7–11]. Israel relatively prevalent Arabs first second generations Jewish immigrants from mid-eastern North Africa virtually non exsistent Jews European origin [7–10]. This was also Mediterranean as, Africa, Italy, Spain Iran, Mexico, South America African-Cape-Coloured people [11–13]. evidence thus would seem suggest predisposition environmentally determined. One could speculate about unique vulnerability due genetic factors combination environmental influences. this work we summarized present day knowledge on analysed possible effects its development. possibility abnormalities lymphoreticular system effect will discussed.