Microvascular Dysfunction in the Context of Diabetic Neuropathy

摘要: Microvascular dysfunction in diabetes plays a crucial role the development of diabetic complications. The skin, as one most accessible organs, serves model for investigation microvascular dysfunction. Several non-invasive, mostly laser-Doppler-based methods have been developed lately to assess function skin. functional changes occur even prediabetic state and become more complex with overt diabetes, being exacerbated by presence peripheral and/or autonomic neuropathy. present article aims at shedding light on implication endothelial neurovascular highlighting contribution different forms