The prevalence and genetics of resistance to commonly used antimicrobial agents in faecal Enterobacteriaceae from children in Bangladesh

摘要: Abstract The present study was undertaken to investigate the occurrence of antibiotic resistance in enteric flora 64 children rural Bangladesh over a 12-month period. The pattern isolates varied throughout year and multiple highest during post monsoon Seventy-three percent had resistant more than three antibiotics year. Resistance streptomycin (78%), followed closely by ampicillin (72%). Of 82 multiply isolates, plasmid DNA demonstrated 75%. Plasmid sizes ranged between 3.7 110 MDa, commonest plasmids were 70, 98 MDa. Complete or partial transferred conjugation from 52% most frequently single plasmids. incompatibility group F11-A (46%) P (22%). Plasmids molecular weight MDa often hybridized with probes those H11 probes. 10 transconjugants digested restriction enzymes digest patterns presence common findings show that there is diverse, mobile, genetic pool genes this community. This reservoir potentially transferable pathogens, major implications for public health diarrhoeal disease control.