DNA polymerase beta can substitute for DNA polymerase I in the initiation of plasmid DNA replication.
作者： J B Sweasy , M Chen , L A Loeb
DOI: 10.1128/JB.177.10.2923-2925.1995
关键词: Molecular biology 、 DNA clamp 、 Polymerase 、 Biology 、 DNA polymerase I 、 DNA polymerase 、 Prokaryotic DNA replication 、 DNA polymerase II 、 DNA polymerase delta 、 DNA replication
摘要: We previously demonstrated that mammalian DNA polymerase beta can substitute for I of Escherichia coli in replication and base excision repair. have now obtained genetic evidence suggesting E. the initiation a plasmid containing pMB1 origin replication. Specifically, we demonstrate with be maintained an polA mutant presence beta. Our results suggest by initiating this from 3' OH terminus RNA-DNA hybrid at
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