Hypothalamic-pituitary-gonadal function in prepubertal boys and girls with chronic renal failure

作者: M. Castellano , A. Turconi , E. Chaler , M.A. Rivarola , A. Belgorosky

DOI: 10.1016/S0022-3476(05)83485-7

关键词: MedicineEndocrine secretionEl NiñoHormonePhysiologyChronic renal failureDialysisEndocrinologyGonadotropin-releasing hormoneInternal medicineTransplantationConservative treatment

摘要: Hypothalamic-pituitary-gonadal function was evaluated in 24 prepubertal children with chronic renal failure (CRF). Among the 17 boys, 5 were receiving conservative treatment and four long-term dialysis. Another eight boys studied 6 months to 3.3 years after transplantation; their ages ranged from 8 15 1/2 years. girls, two patients five dialysis; 3 11 2 months. In CRF, but not those transplantation, mean serum follicle-stimulating hormone 60 minutes administration of gonadotropin releasing (GnRH) lower than 18 control (mean±SD: 2.53±1.34 vs 6.25±2.84 IU/L, respectively; p

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