Procalcitonin is a valuable prognostic marker in cardiac surgery but not specific for infection.

摘要: BACKGROUND The prognostic value of elevated serum levels procalcitonin (PCT) in patients early after cardiac surgery on cardiopulmonary bypass (CPB) remains unclear. In a prospective study, we investigated whether PCT is useful as marker with respect to mortality, complications and infections, specific for occurrence infections. METHODS Within 8 months, subset 80 high-risk (APACHE II-score: 25.1 +/- 4.7 (mean SD)) out consecutive cohort 776 was investigated. Demographic data, operative data clinical endpoints (mortality, infection, severe complication) were documented. Serum analyzed preoperatively at postoperative day 1. RESULTS Hospital mortality this group 21.3 %, infections occurred 33.8 % 58.8 the patients. Preoperative normal all Postoperative increased non-survivors compared survivors (34.3 7.0 ng/ml vs. 15.9 4.9 ng/ml; p < 0.05), (30.3 6.7 5.5 1.4 0.05) (38.4 11.3 10.8 1.6 0.05). Area under receiver operating characteristic curve predictor 0.772 (95 %-confidence-interval (CI): 0.651 - 0.894), 0.720 %-CI: 0.603 0.837) 0.861 0.779 0.943), respectively. not different infectious non-infectious complications. CONCLUSIONS High are associated using therefore provide valuable marker. However, does discriminate between