Serum concentrations of procalcitonin after cardiac surgery.

作者: Cristina Prat , Pilar Ricart , Xavier Ruyra , Josep Domínguez , Jordi Morillas

DOI: 10.1111/J.1540-8191.2008.00658.X

关键词: Systemic inflammatory response syndromeProspective cohort studyAnesthesiaValve replacementProcalcitoninPopulationIntensive care unitCardiopulmonary bypassSurgeryCardiac surgeryMedicine

摘要: Abstract Background and Aim: Monitorization of complications in patients underlying cardiac surgery may be difficult because cardiopulmonary bypass (CPB) can lead to a systemic inflammatory response syndrome exposure blood nonphysiological surfaces. The purpose the study was establish baseline levels procalcitonin (PCT) after our population order analyze possible induction that might interfere with diagnosis infection by PCT. Methods: Serum samples from undergoing coronary artery grafting or valve replacement were collected at time admission intensive care unit, as well first second postoperative days. Patients followed for development complications. PCT measured immunoluminometric assay. Results: mean values significantly higher day all groups except control group. No increased found related neither duration CPB, nor aortic clamping. Only who presented had immediately (p = 0.004), < 0.0001), 0.0001) respect those recovered uneventfully. Conclusions: A slight transient increase observed surgery. Significant elevation only when present.

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