Procalcitonin: a useful biomarker to discriminate infection after cardiopulmonary bypass in children.

摘要: OBJECTIVE To determine whether procalcitonin discriminates between postcardiopulmonary bypass inflammatory syndrome and infectious complication in children better than does C-reactive protein. DESIGN Prospective study of admitted to the intensive care unit after cardiopulmonary bypass. PATIENTS Classified according a diagnosis systemic response bacterial infection or but no infection. Two hundred thirty-one cases were recruited. MEASUREMENT AND MAIN RESULTS Procalcitonin, protein, leukocyte count measured daily from surgery until day 3. Twenty-two patients infected (9.5%). Significant differences detected values group vs. noninfected group, especially at 2 (p = .000). There protein values. The optimal cutoff for was >2 ng/mL 1 above 4 2. greater sensitivity specificity with as an predictor. CONCLUSION Procalcitonin is useful Because kinetics are different patients, diagnose should be normal cutoff.