Alternation in dopamine D2-like and metabotropic glutamate type 5 receptor density caused by differing housing conditions during abstinence from cocaine self-administration in rats.

作者: Małgorzata Frankowska , Joanna Miszkiel , Lucyna Pomierny-Chamioło , Bartosz Pomierny , Giuseppe Giannotti

DOI: 10.1177/0269881118821113

关键词: Metabotropic receptorGlutamate receptorSelf-administrationReceptorAbstinenceDopamine receptor D2EndocrinologyDrug AbstinenceSubstance abuseInternal medicineMedicine

摘要: Background:Environmental conditions have an important function in substance use disorder, increasing or decreasing the risks of relapse. Several studies strongly support role dopamine D2...

参考文章(80)
Osnat Ben-Shahar, Ilona Obara, Alexis W. Ary, Natalie Ma, Mario A. Mangiardi, Robert L. Medina, Karen K. Szumlinski, Extended daily access to cocaine results in distinct alterations in Homer 1b/c and NMDA receptor subunit expression within the medial prefrontal cortex. Synapse. ,vol. 63, pp. 598- 609 ,(2009) , 10.1002/SYN.20640
N.D. Volkow, R.D. Baler, Addiction science: Uncovering neurobiological complexity. Neuropharmacology. ,vol. 76, pp. 235- 249 ,(2014) , 10.1016/J.NEUROPHARM.2013.05.007
Udi E. Ghitza, Haifeng Zhai, Ping Wu, Mikko Airavaara, Yavin Shaham, Lin Lu, Role of BDNF and GDNF in drug reward and relapse: a review. Neuroscience & Biobehavioral Reviews. ,vol. 35, pp. 157- 171 ,(2010) , 10.1016/J.NEUBIOREV.2009.11.009
Lucyna Pomierny-Chamiolo, Joanna Miszkiel, Małgorzata Frankowska, Bartosz Pomierny, Ewa Niedzielska, Irena Smaga, Fabio Fumagalli, Małgorzata Filip, Withdrawal from Cocaine Self-administration and Yoked Cocaine Delivery Dysregulates Glutamatergic mGlu5 and NMDA Receptors in the Rat Brain Neurotoxicity Research. ,vol. 27, pp. 246- 258 ,(2015) , 10.1007/S12640-014-9502-Z
Robert C. Twining, Matthew Bolan, Patricia S. Grigson, Yoked delivery of cocaine is aversive and protects against the motivation for drug in rats. Behavioral Neuroscience. ,vol. 123, pp. 913- 925 ,(2009) , 10.1037/A0016498
Alessandro Sale, Nicoletta Berardi, Lamberto Maffei, Enrich the environment to empower the brain Trends in Neurosciences. ,vol. 32, pp. 233- 239 ,(2009) , 10.1016/J.TINS.2008.12.004
Gaetano Di Chiara, Nucleus accumbens shell and core dopamine: differential role in behavior and addiction Behavioural Brain Research. ,vol. 137, pp. 75- 114 ,(2002) , 10.1016/S0166-4328(02)00286-3
Rajita Sinha, How does stress increase risk of drug abuse and relapse Psychopharmacology. ,vol. 158, pp. 343- 359 ,(2001) , 10.1007/S002130100917
Pedro Garrido, M De Blas, G Ronzoni, Isabel Cordero, María Antón, E Giné, A Santos, A Del Arco, G Segovia, F Mora, None, Differential effects of environmental enrichment and isolation housing on the hormonal and neurochemical responses to stress in the prefrontal cortex of the adult rat: relationship to working and emotional memories Journal of Neural Transmission. ,vol. 120, pp. 829- 843 ,(2013) , 10.1007/S00702-012-0935-3