ADMINISTRATION OF LACTOBACILLUS HELVETICUS NS8 IMPROVES BEHAVIORAL, COGNITIVE, AND BIOCHEMICAL ABERRATIONS CAUSED BY CHRONIC RESTRAINT STRESS

作者: S. Liang , T. Wang , X. Hu , J. Luo , W. Li

DOI: 10.1016/J.NEUROSCIENCE.2015.09.033

关键词: Chronic stressSerotoninBrain-derived neurotrophic factorPsychologyCitalopramAdrenocorticotropic hormoneCorticosteroneSerotonin reuptake inhibitorInternal medicineEndocrinologyLactobacillus helveticus

摘要: Increasing numbers of studies have suggested that the gut microbiota is involved in the pathophysiology of stress-related disorders. Chronic stress can cause behavioral, cognitive, biochemical, and gut microbiota aberrations. Gut bacteria can communicate with the host through the microbiota–gut–brain axis (which mainly includes the immune, neuroendocrine, and neural pathways) to influence brain and behavior. It is hypothesized that administration of probiotics can improve chronic-stress-induced depression. In order to examine this …

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