Celiac disease and its endocrine and nutritional implications on male reproduction

摘要: The problem of the interference celiac disease (CD) with male reproductive system is made evident both by recognized adverse effects on female reproduction and multifactorial nature disease. It important to consider CD as a condition since its diverse can be modulated, besides gluten, different concurrent genetic environmental factors. patient has greater risk infertility other disturbances, well incidence hypoandrogenism. In this paper problems associated endocrine disorders deficiencies micronutrients are discussed. Affected males show picture tissue resistance androgens. Moreover, attention should paid increases FSH prolactin; these not and/or impotence, but they may indicate an imbalance at hypothalamus-pituitary level, general health: example increased osteoporosis in patients. Hormone alterations reversible upon start gluten-free diet, emphasizing importance early diagnosis; performed case clinical suspicion, e.g., unexplained As regards nutritional aspects, folic acid deficiency affect rapidly proliferating tissues, such embryo seminiferous epithelium. More fat-soluble vitamins, A E, observed CD. Vitamin for Sertoli cell function spermatogenetic phases. E supports correct differentiation epidydimal epithelium, spermatid maturation secretion proteins prostate. Therefore, patients considered vulnerable subjects; thus, detection biomarkers andrological or endocrinological dysfunctions trigger timely strategies prevention treatment.