Diagnosis of HIV-associated tuberculosis.

作者: Susan E. Dorman

DOI: 10.1097/COH.0000000000000497

关键词: MedicineCase detectionIntensive care medicineDiagnostic testMycobacterium tuberculosis Nucleic AcidTuberculosisDrug susceptibilityTuberculosis diagnosisHuman immunodeficiency virus (HIV)Extramural

摘要: Purpose of review The current highlights recent advances in tuberculosis (TB) diagnostics that are relevant for clinicians engaged the care HIV-positive adults. Recent findings first section focuses on newly available tools, highlighting progress. second new diagnostic approaches not yet widely or implemented, but have considerable potential to improve management TB/HIV coinfected persons. final speculates about future directions may be fruitful. Summary Advances Mycobacterium nucleic acid amplification-based genotypic tests stand case detection and drug susceptibility testing near term. Identification human gene expression signatures associated with TB and/or risk, identification novel M. targets coupled exploitation biosensor technology transform diagnosis future.

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