作者: Susan E. Dorman
DOI: 10.1097/COH.0000000000000497
关键词: Medicine 、 Case detection 、 Intensive care medicine 、 Diagnostic test 、 Mycobacterium tuberculosis Nucleic Acid 、 Tuberculosis 、 Drug susceptibility 、 Tuberculosis diagnosis 、 Human immunodeficiency virus (HIV) 、 Extramural
摘要: Purpose of review The current highlights recent advances in tuberculosis (TB) diagnostics that are relevant for clinicians engaged the care HIV-positive adults. Recent findings first section focuses on newly available tools, highlighting progress. second new diagnostic approaches not yet widely or implemented, but have considerable potential to improve management TB/HIV coinfected persons. final speculates about future directions may be fruitful. Summary Advances Mycobacterium nucleic acid amplification-based genotypic tests stand case detection and drug susceptibility testing near term. Identification human gene expression signatures associated with TB and/or risk, identification novel M. targets coupled exploitation biosensor technology transform diagnosis future.