Tissue distribution of the receptor for plasma retinol-binding protein

摘要: The tissue distribution of the retinol-binding-protein receptor has been studied by using a cell-free binding assay. High activity was found in placenta, retina pigment epithelial cells, bone marrow and kidneys. Specific also small intestines, spleen liver, to lesser extent lung. Scatchard analysis revealed that difference due variations level not affinity changes. When kidneys were separated into cortex medulla we almost all specific present recovered cortex. choroid plexus, an important site delivery nutrients cerebrospinal fluid, expressed very high activity. pineal gland, which shown store vitamin A, showed Testes from immature animals higher than testes mature rabbits. Cultured undifferentiated kidney keratinocytes about 40 times differentiated cells. Skin fibroblasts demonstrated no In conclusion, data presented this report show varies considerably between cell types. observed agrees well with knowledge on retinol function metabolism various