Human papillomavirus types 6 and 11 mRNAs from genital condylomata acuminata.

摘要: We have identified and mapped a number of RNA species human papillomavirus types 6 11 from condylomata acuminata by the electron microscopic R-loop technique. Each early (E)- late (L)-region open reading frames (ORFs) deduced DNA sequences was represented in one or more transcripts. In addition, that could encode modulator replication repressor transcription, functions recently genetically similar bovine type 1, were also detected. Some ORFs 5' proximal transcripts, whereas others not any species, suggesting internal initiation translation might be required to gain access these latter ORFs. Virtually all transcripts had their ends located E region polyadenylated at two sites, i.e., end L region. The great majority RNAs derived genome, with approximately 50 100 times abundant than others. For most RNAs, near nucleotide 700; minor populations 1200. By correlating our mapping data genomic as well available structures cDNA several papillomaviruses, we predict mRNA splice donor acceptor sites suggest papillomaviruses sophisticated usage through alternative promoters, polyadenylation sites.