Effects of motivation of the patient on indices of exercise capacity in chronic heart failure.

作者: A. L. Clark , P. A. Poole-Wilson , A. J. Coats

DOI: 10.1136/HRT.71.2.162

关键词: Exercise limitationMedicineVO2 maxHeart failureOxygenExercise capacityAnimal scienceSurgeryPhysical exerciseBreathingAnaerobic exercise

摘要: BACKGROUND--Measurement of variables metabolic gas exchange during exercise is widely used to assess the severity heart failure. The derived however, are potentially dependent on motivation patient and duration exercise. METHODS--The data from tests in 23 patients with exertional breathlessness were analysed derive following three common indices tolerance: anaerobic threshold, extrapolated maximum oxygen consumption, ventilation carbon dioxide production slope. reanalysed points first 90% subsequent exercise, 75%, finally up point where a respiratory ratio 1 was reached. RESULTS--The mean (SEM) threshold lower when computed than 100% (13.2 (1.0) ml/kg/min v 12.5 (1.0), p < 0.001) still 75% (11.4 (0.7), = 0.006 90%). Extrapolated consumption unchanged data, but higher (25.4 (2.1) at 28.6 0.001). slope became progressively shallower measured eventual exercise: 32.3 (1.5) 30.0 90%, 0.001; 28.3 0.001 90%. At 1, final calculation, (11.8 (0.9), 0.005) (27.5 (1.4), CONCLUSIONS--Anaerobic tends overestimate limitation tend underestimate severity. most reliable measures, independent effort provided that encouraged exceeds 1.

参考文章(20)
Marco Metra, Riccardo Raddino, Livio Dei Cas, Odoardo Visioli, Assessment of peak oxygen consumption, lactate and ventilatory thresholds and correlation with resting and exercise hemodynamic data in chronic congestive heart failure The American Journal of Cardiology. ,vol. 65, pp. 1127- 1133 ,(1990) , 10.1016/0002-9149(90)90326-V
Andrew Lawrence Clark, Philip Alexander Poole-Wilson, Andrew Justin Stewart Coats, Relation between ventilation and carbon dioxide production in patients with chronic heart failure. Journal of the American College of Cardiology. ,vol. 20, pp. 1326- 1332 ,(1992) , 10.1016/0735-1097(92)90244-H
Jere H. Mitchell, Brian J. Sproule, Carleton B. Chapman, THE PHYSIOLOGICAL MEANING OF THE MAXIMAL OXYGEN INTAKE TEST1 Journal of Clinical Investigation. ,vol. 37, pp. 538- 547 ,(1958) , 10.1172/JCI103636
D P Lipkin, J Perrins, P A Poole-Wilson, Respiratory gas exchange in the assessment of patients with impaired ventricular function. Heart. ,vol. 54, pp. 321- 328 ,(1985) , 10.1136/HRT.54.3.321
Marco Metra, Livio Dei Cas, Gaia Panina, Odoardo Visioli, Exercise hyperventilation chronic congestive heart failure, and its relation to functional capacity and hemodynamics American Journal of Cardiology. ,vol. 70, pp. 622- 628 ,(1992) , 10.1016/0002-9149(92)90202-A
John R. Wilson, Donna M. Mancini, Nancy Ferraro, Joseph Egler, Effect of dichloroacetate on the exercise performance of patients with heart failure Journal of the American College of Cardiology. ,vol. 12, pp. 1464- 1469 ,(1988) , 10.1016/S0735-1097(88)80010-X
N.J.H. Davies, D.M. Denison, The measurement of metabolic gas exchange and minute volume by mass spectrometry alone Respiration Physiology. ,vol. 36, pp. 261- 267 ,(1979) , 10.1016/0034-5687(79)90029-X
G. S. Francis, Clinical aspects of heart failure Current Opinion in Cardiology. ,vol. 1, pp. 347- 353 ,(1986) , 10.1097/00001573-198605000-00004