Prevalence of Antibody against Non-A, non-B Hepatitis Virus in Japanese Patients with Hepatocellular Carcinoma

作者: Showgo Ohkoshi , Hideo Kojima , Hironobu Tawaraya , Tohru Miyajima , Tomoteru Kamimura

DOI: 10.1111/J.1349-7006.1990.TB02605.X

关键词: Hepatitis C virusViral diseaseVirusVirologyHepatitisHBsAgAntibodyHepatocellular carcinomaBlood transfusionMedicineCancer researchOncology

摘要: Antibodies against a possible causative agent of non-A, non-B hepatitis, hepatitis C virus (HCV), in Japanese patients with hepatocellular carcinoma were analyzed using the enzyme-linked immunosorbent assay (ELISA) system from Ortho Diagnostic Systems, Japan. Fifty 58 cases B surface antigen (HBsAg)-negative positive for antibody (86%) and 8 42 HBsAg-positive (19%). Among HBsAg-negative carcinoma, prevalence was greater among those who had received blood transfusion (97%) than no history (70%). Only 3 54 cancers other found to be antibody-positive (5.6%) all three transfusion. These results show close relationship between presence anti-HCV

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