Diagnostic assessment of platelet disorders: what are the challenges to standardization?

摘要: The platelet disorders are a group of heterogeneous, congenital and acquired bleeding associated with impaired function. There is growing interest in standardizing the assessment these disorders, but this challenged by their heterogeneity, absence widely accepted diagnostic criteria, inconsistency laboratory testing practices for disorders. Symptoms commonly include rapid-onset hemostatic challenges, peripartum bleeding, menorrhagia, epistaxis, gingival increased bruising. Attempts have been made to standardize symptoms, using clinical tools scores. However, there currently no standardized available proven utility apart from tool specifically designed assess Quebec disorder. several efforts improve These guidelines International Society on Thrombosis Haemostasis Clinical Laboratory Standards Institute. Recent research indicates that application tests individuals referred problems has valuable utility. This provided further incentive approaches evaluation worldwide.