作者: Andrew J. M. Howden , Edgar Huitema
关键词: Pathogen-associated molecular pattern 、 Immune system 、 Pattern recognition receptor 、 Plant Immunity 、 Effector 、 Neuroscience 、 Immunology 、 Biology 、 Immunity 、 Signalling 、 Proteomics
摘要: Plant-pathogen interactions feature complex signalling exchanges between host and microbes that ultimately determine association outcomes. Plants deploy Pattern Recognition Receptors (PRRs) to perceive Pathogen Associated Molecular Patterns (PAMPs), mount Triggered Immunity (PTI) fend off potential pathogens. In recent years an increasing number of defence components have been identified along with a mechanistic understanding their regulation during immune responses. Post-translational modifications (PTMs) are now thought play crucial role in regulating signalling. bid suppress PTI infect host, pathogens evolved large repertoires effectors trigger susceptibility allow colonization tissues. While great progress has made elucidating networks plants the activities suppression, critical gap exists our effector mechanism-of-action. Given importance PTMs signalling, we will explore question: how do modify post-translational status proteins thus interfere processes required for immunity? We consider emerging proteomics based experimental strategies may help us answer this important question open pathogens’ black box.