Innate inflammatory signals induced by various pathogens differentially dictate the IFN-I dependence of CD8 T cells for clonal expansion and memory formation.

作者: Lucas J. Thompson , Ganesh A. Kolumam , Sunil Thomas , Kaja Murali-Krishna

DOI: 10.4049/JIMMUNOL.177.3.1746

关键词: VirologyLymphocytic choriomeningitisVesicular stomatitis virusAntigenAdjuvantInterleukin 21BiologyMolecular biologyCell growthVirusCytotoxic T cell

摘要: … and IFN-IR OVA-specific OT-1 CD8 T cells with a fixed-number of OVA-peptide-pulsed dendritic cells along with adjuvant effect provided by LCMV, VV, VSV, or LM. Both WT and IFN-IR …

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