Impaired cell mediated immunity in haemophilia in the absence of infection with human immunodeficiency virus.

摘要: The cell mediated immune response was evaluated in vivo 29 patients with clinically severe haemophilia by means of the dinitrochlorobenzene skin test. All had a below median normal value, and 19 on or lower limit range. There no difference between positive negative for human immunodeficiency virus (HIV; formerly known as T lymphotropic III lymphadenopathy associated virus). In whole group, seronegative (n = 17), there an inverse relation exposure to clotting factor response. seropositive 12) such association apparent. This study shows that concentrate impairs new antigen absence infection HIV.