Regulation of HMGB1 release by autophagy

作者： Jacqueline Thorburn , Arthur E. Frankel , Andrew Thorburn

关键词: Mechanism of action 、 HMGB1 、 Cell biology 、 Epidermal growth factor 、 Diphtheria toxin 、 Apoptosis 、 Biology 、 Autophagy 、 Immune system 、 Programmed cell death

摘要: … tumor cells release the immune modulator HMGB1 after treatment with anticancer drugs, they can activate a tumor-… selective release of HMGB1 rather than just induction of necrosis. We …