Hyperthermy increase the phosphorylation of deoxycytidine in the membrane phospholipid precursors and decrease its incorporation into DNA.
作者： Gergely Keszler , Zsolt Csapó , Tatjana Spasokoutskaja , Maria Sasvari-Székely , Sula Virga
关键词: Kinase 、 Deoxyadenosine 、 Chemistry 、 Nucleoside 、 Thymidine kinase 、 Biochemistry 、 DNA repair 、 DNA 、 DNA synthesis 、 DNA damage
摘要: Concerning our results, dCK seems to be the most important deoxynucleoside kinase in resting phase cells, or cells with DNA damages repaired. The damage might induced by different nucleoside analogues, inhibitors of synthesis. Deoxyadenosine and its their triphosphates are repair itself, pushing corresponding salvage a “more” active form, probably secondary modification enzyme, produce deoxynucleotides for repairing DNA.
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