Three-dimensional models of cancer for pharmacology and cancer cell biology: capturing tumor complexity in vitro/ex vivo

作者: John A. Hickman , Ralph Graeser , Ronald de Hoogt , Suzana Vidic , Catarina Brito

DOI: 10.1002/BIOT.201300492

关键词: Drug discoveryCancerStem cellPharmacologyBiologyStromal cellEx vivoIn vitroBreast cancerCancer cell

摘要: Cancers are complex and heterogeneous pathological “organs” in a dynamic interplay with their host. Models of human cancer in vitro, used in cancer biology and drug discovery, are …

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