Maltreatment of Strongyloides infection: Case series and worldwide physicians-in-training survey

作者: David R. Boulware , William M. Stauffer , Brett R. Hendel-Paterson , Jaime Luís Lopes Rocha , Raymond Chee-Seong Seet

DOI: 10.1016/J.AMJMED.2006.05.072

关键词: MedicineHealth careContinuing medical educationStrongyloides stercoralisSurgeryPediatricsRelative riskStrongyloidiasisStrongyloidesEosinophiliaHelminthiasis

摘要: Abstract Background Strongyloidiasis infects hundreds of millions people worldwide and is an important cause mortality from intestinal helminth infection in developed countries. The persistence infection, increasing international travel, lack familiarity by health care providers, potential for iatrogenic hyperinfection all make strongyloidiasis emerging infection. Methods Two studies were performed. A retrospective chart review Strongyloides stercoralis cases identified through microbiology laboratory records 1993-2002 was conducted. Subsequently, 363 resident physicians 15 training programs queried with a case scenario strongyloidiasis, presenting immigrant wheezing eosinophilia. evaluation focused on recognition diagnostic recommendations. Results In 151 cases, stool ova parasite sensitivity poor (51%), eosinophilia (>5% or >400 cells/μL) commonly present (84%). Diagnosis averaged 56 months (intra-quartile range: 4-72 months) after immigration. Presenting complaints nonspecific, although 10% presented wheezing. Hyperinfection occurred 5 patients prescribed corticosteroids, 2 deaths. Treatment errors more often among providers unfamiliar (relative risk error: 8.4; 95% confidence interval, 3.4-21.0; P Conclusions US patients. Diagnostic consideration should occur appropriate exposure, nonspecific symptoms including wheezing, relative eosinophils/μL). residents’ knowledge limited places immigrants danger. Information about be included continuing medical education programs.

参考文章(35)
Peter F. Weller, Leo X. Liu, Strongyloidiasis and other intestinal nematode infections. Infectious Disease Clinics of North America. ,vol. 7, pp. 655- 682 ,(1993) , 10.1016/S0891-5520(20)30548-1
Wanchai Maleewong, Pewpan M Intapan, Somsak Nilpan, Supranee Veerakul, Praphasri Jongsuksuntigul, Seri Singthong, Thitima Wongsaroj, Prevalence of Strongyloides stercoralis infection in northeastern Thailand (agar plate culture detection). Journal of the Medical Association of Thailand Chotmaihet thangphaet. ,vol. 86, pp. 737- 741 ,(2003)
Paul R. DeLay, Joseph D. Mahood, Helen Ortega, Kenneth A. Borchardt, Karen Hipkins, Gisela Schecter, John Doss, Jeffrey Newman, Robert H. Gelber, Intestinal parasites in Southeast Asian refugees. Western Journal of Medicine. ,vol. 135, pp. 93- 96 ,(1981)
THERESA W. GYORKOS, ROBERT M. GENTA, PIERRE VIENS, J. DICK MACLEAN, SEROEPIDEMIOLOGY OF STRONGYLOIDES INFECTION IN THE SOUTHEAST ASIAN REFUGEE POPULATION IN CANADA American Journal of Epidemiology. ,vol. 132, pp. 257- 264 ,(1990) , 10.1093/OXFORDJOURNALS.AJE.A115655
Peter D. Walzer, George Kilgore, James E. Milder, John G. Banwell, Marilyn Klein, Ruby Parker, Epidemiologic features of Strongyloides stercoralis infection in an endemic area of the United States. American Journal of Tropical Medicine and Hygiene. ,vol. 31, pp. 313- 319 ,(1982) , 10.4269/AJTMH.1982.31.313
Gwendolyn Halford, County and City Data Book Journal of Business & Finance Librarianship. ,vol. 5, pp. 61- 67 ,(1999) , 10.1300/J109V05N02_08
John H. Wehner, Carl M. Kirsch, Frank T. Kagawa, William A. Jensen, Anthony C. Campagna, Marianna Wilson, The Prevalence and Response to Therapy of Strongyloides stercoralis in Patients With Asthma From Endemic Areas Chest. ,vol. 106, pp. 762- 766 ,(1994) , 10.1378/CHEST.106.3.762
P. R. Hira, F. Al-Ali, H. M. Shweiki, N. A. Abdella, M. Johny, I. Francis, J. Iqbal, R. Thompson, F. Nevar, Strongyloidiasis: challenges in diagnosis and management in non-endemic Kuwait. Annals of Tropical Medicine and Parasitology. ,vol. 98, pp. 261- 270 ,(2004) , 10.1179/000349804225003299
Steven L. Berk, Clinical and Epidemiologic Features of Strongyloidiasis Archives of Internal Medicine. ,vol. 147, pp. 1257- 1261 ,(1987) , 10.1001/ARCHINTE.1987.00370070071011
Benjamin J. Leeman, Manuel R. Cabrera, No Association Found Between Strongyloides Infestation and Asthma Journal of Asthma. ,vol. 32, pp. 57- 62 ,(1995) , 10.3109/02770909509089500