New frontiers in cell competition†
作者： Simon de Beco , Marcello Ziosi , Laura A. Johnston
DOI: 10.1002/DVDY.23783
关键词: Cell biology 、 Cell signaling 、 Regulation of gene expression 、 Competition (economics) 、 Biology 、 Organism 、 Cell 、 Cell fate determination 、 Cellular differentiation 、 Cellular communication 、 Neuroscience
摘要: Cellular communication is at the heart of animal development, and guides specification cell fates, movement cells within between tissues, coordinated arrangement different body parts. During organ tissue growth, cell-cell plays a critical role in decisions that determine whether survive to contribute organism. In this review, we discuss recent insights into competition, social cellular phenomenon selects fittest tissue, as such potentially contributes regulation its growth final size. The field competition has seen huge explosion study last several years, facilitated by increasingly sophisticated genetic molecular technology available Drosophila driven relevance stem biology human cancer.
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