BILN 2061: a major step toward new therapeutic strategies in hepatitis C
作者： Tarik Asselah , Patrick Marcellin
DOI: 10.1016/J.JHEP.2004.05.004
关键词: Hepatitis C 、 Virology 、 Medicine
摘要:
journal-of-hepatology.eu
elsevier.com
sci-hub.se 参考文章(16)
Takanobu Kato, Tomoko Date, Michiko Miyamoto, Akihiro Furusaka, Katsutoshi Tokushige, Masashi Mizokami, Takaji Wakita, Efficient replication of the genotype 2a hepatitis C virus subgenomic replicon Gastroenterology. ,vol. 125, pp. 1808- 1817 ,(2003) , 10.1053/J.GASTRO.2003.09.023
Markus Reiser, Holger Hinrichsen, Yves Benhamou, Roel Sentjens, Heiner Wedemeyer, Luis Calleja, Xavier Forns, Jens Croenlein, Chan Yong, Gerhard Nehmiz, Gerhard Steinmann, 136 Antiviral effect of BILN 2061, a novel HCV serine protease inhibitor, after oral treatment over 2 days in patients with chronic hepatitis C, non-genotype 1 Hepatology. ,vol. 38, pp. 221- 221 ,(2003) , 10.1016/S0270-9139(03)80179-9
Christian Steinkühler, Gabriella Biasiol, Mirko Brunetti, Andrea Urbani, Uwe Koch, Riccardo Cortese, Antonello Pessi, Raffaele De Francesco, Product inhibition of the hepatitis C virus NS3 protease. Biochemistry. ,vol. 37, pp. 8899- 8905 ,(1998) , 10.1021/BI980313V
Patrick Marcellin, Tarik Asselah, Nathalie Boyer, Fibrosis and disease progression in hepatitis C Hepatology. ,vol. 36, pp. s47- s56 ,(2002) , 10.1053/JHEP.2002.36993
Eileen Foy, Kui Li, Chunfu Wang, Rhea Sumpter Jr, Masanori Ikeda, Stanley M Lemon, Michael Gale Jr, Regulation of Interferon Regulatory Factor-3 by the Hepatitis C Virus Serine Protease Science. ,vol. 300, pp. 1145- 1148 ,(2003) , 10.1126/SCIENCE.1082604
D Dhumeaux, Treatment of hepatitis C. The 2002 French consensus Gut. ,vol. 52, pp. 1784- 1787 ,(2003) , 10.1136/GUT.52.12.1784
Robert A Love, Hans E Parge, John A Wickersham, Zdenek Hostomsky, Noriyuki Habuka, Ellen W Moomaw, Tsuyoshi Adachi, Zuzana Hostomska, The Crystal Structure of Hepatitis C Virus NS3 Proteinase Reveals a Trypsin-like Fold and a Structural Zinc Binding Site Cell. ,vol. 87, pp. 331- 342 ,(1996) , 10.1016/S0092-8674(00)81350-1
Keril J Blight, Alexander A Kolykhalov, Charles M Rice, Efficient Initiation of HCV RNA Replication in Cell Culture Science. ,vol. 290, pp. 1972- 1974 ,(2000) , 10.1126/SCIENCE.290.5498.1972
J.L Kim, K.A Morgenstern, C Lin, T Fox, M.D Dwyer, J.A Landro, S.P Chambers, W Markland, C.A Lepre, E.T O'Malley, S.L Harbeson, C.M Rice, M.A Murcko, P.R Caron, J.A Thomson, Crystal structure of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide. Cell. ,vol. 87, pp. 343- 355 ,(1996) , 10.1016/S0092-8674(00)81351-3
Caterina Trozzi, Linda Bartholomew, Alessandra Ceccacci, Gabriella Biasiol, Laura Pacini, Sergio Altamura, Frank Narjes, Ester Muraglia, Giacomo Paonessa, Uwe Koch, Raffaele De Francesco, Christian Steinkuhler, Giovanni Migliaccio, In vitro selection and characterization of hepatitis C virus serine protease variants resistant to an active-site peptide inhibitor Journal of Virology. ,vol. 77, pp. 3669- 3679 ,(2003) , 10.1128/JVI.77.6.3669-3679.2003