作者: B Kjessler , S.G.O Johansson , M Sherman , K.-H Gustavson , G Hultquist
DOI: 10.1016/S0140-6736(75)91495-6
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摘要: Alpha-fetoprotein (A.F.P,) levels were found to ge significantly raised in maternal serum and amniotic-fluid samples form the 16th 18th weeks of gestation a woman with an apparently normal fetus but histological evidence congenital nephrosis Finnish type. Increased concentrations A.F.P. early pregnancy living are therefore not specific for neural-tube defects; More likely they result from fetal circulation. Extended investigations, including kidney morphology, should be done cases apparent false-positive tests.