The CYP2C9 genotype does not influence sildenafil pharmacokinetics in healthy volunteers
作者： A JETTER , A LAZAR , E SCHOMIG , U FUHR , M KINZIGSCHIPPERS
DOI: 10.1016/J.CLPT.2005.08.005
关键词:
摘要:
nature.com
sci-hub.se 参考文章(5)
R. Hyland, E. G. H. Roe, B. C. Jones, D. A. Smith, Identification of the cytochrome P450 enzymes involved in the N‐demethylation of sildenafil British Journal of Clinical Pharmacology. ,vol. 51, pp. 239- 248 ,(2001) , 10.1046/J.1365-2125.2001.00318.X
R. I. Shader, L. L. Von Moltke, D. J. Greenblatt, J. S. Warrington, In vitro biotransformation of sildenafil (Viagra): identification of human cytochromes and potential drug interactions. Drug Metabolism and Disposition. ,vol. 28, pp. 392- 397 ,(2000)
Alexander Jetter, Martina Kinzig-Schippers, Andreas Skott, Andreas Lazar, Dorota Tomalik-Scharte, Julia Kirchheiner, Monika Walchner-Bonjean, Ursula Hering, Verena Jakob, Michael Rodamer, Wafa� Jabrane, Dirk Kasel, J�rgen Brockm�ller, Uwe Fuhr, Fritz S�rgel, Cytochrome P450 2C9 phenotyping using low-dose tolbutamide. European Journal of Clinical Pharmacology. ,vol. 60, pp. 165- 171 ,(2004) , 10.1007/S00228-004-0754-Z
J KIRCHHEINER, J BROCKMOLLER, Clinical consequences of cytochrome P450 2C9 polymorphisms. Clinical Pharmacology & Therapeutics. ,vol. 77, pp. 1- 16 ,(2005) , 10.1016/J.CLPT.2004.08.009
Alexander Jetter, Martina Kinzig‐Schippers, Monika Walchner‐Bonjean, Ursula Hering, Jürgen Bulitta, Philipp Schreiner, Fritz Sörgel, Uwe Fuhr, Effects of grapefruit juice on the pharmacokinetics of sildenafil. Clinical Pharmacology & Therapeutics. ,vol. 71, pp. 21- 29 ,(2002) , 10.1067/MCP.2002.121236