作者: Loren D. Walensky , Gregory Bird
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摘要: The invention provides structurally constrained viral peptides for use as therapeutic and vaccination agents, the production of antibodies in a number applications including agents. further methods kits instant invention. is based, at least part, on result provided herein demonstrating that hydrocarbon stapled helical display excellent proteolytic, acid, thermal stability, restore native structure peptide, are highly effective interfering with fusogenic process, possess superior pharmacokinetic properties compared to corresponding unmodified peptides.